AI & I

New York Times journalist Kevin Roose has 18 new friends—none of whom are human. 
Kevin formed a collection of “friends”—AI personas with distinct personalities and backstories—using apps like Kindroid and Nomi. Among these were fitness guru Jared, San Francisco-based therapist P...

Nick Dobos, maker of the #1 programming GPT, on prompt-gramming with AI
You can go from having an idea to deploying a live website in minutes.

All you have to do is prompt Grimoire, the number-one custom GPT for programming, with an image or even a single word about your idea. A...

The future of AI technology isn’t just faster or more powerful—it’s empathetic. My guest for this episode, Alan Cowen, is leading the charge with the first-ever emotionally intelligent AI.

Alan is the co-founder and CEO of Hume, an AI research laboratory developing models traine...

Learn how to use philosophy to run your business more effectively
Reid Hoffman thinks a masters in philosophy will help you run your business better than an MBA.

Reid is the cofounder of LinkedIn, a partner at venture capital firm Greylock Partners, the host of the Masters of Sc...

Seth-Stephens Davidowitz wrote a book in 30 days—and he did it with ChatGPT.
Seth is a data scientist, economist, and author who challenged himself to write a book—Who Makes the NBA?—in less than 1 month after realizing how fast he could work by using ChatGPT plugin Advanced Data...

Nicholas Thorne is building Squarespace for the AI age. It’s called Audos, and it’s an AI chatbot to help any entrepreneur go from idea to:
- Pitch deck
- Working website
- Custom GPT
- User interviews with real customers
All in just a few minutes. And he did it using ChatGPTapp....

Antidepressants changed my life.

I have OCD and antidepressants did what nearly a decade of therapy, meditation, and supplements couldn’t: they allowed me to live my life without being in a 24/7 spiral. (Bonus: they actually made therapy and meditation far more helpful once they...

You can build and run a one-person internet business that earns half a million in annual revenue—with AI.
Ben Tossell showed me exactly how in this episode. Ben is the founder of Ben’s Bites—one of the best daily AI newsletters out there, which I love reading every day—and an inv...

I made the greatest trade of my life with Jesse Beyroutey in 2019. We bought Nvidia shares when they were trading at $33. They’re worth nearly $800 today.
I sat down with Jesse to top that trade in 90 minutes using Gemini Pro 1.5’s incredible 1 million token context window—and ma...

You can break into Hollywood with a movie you made alone in your room without using a single camera. Dave Clark showed me how live on this show.
Dave Clark is a film director and commercial director with experience working with brands like HP and Intel who is now experimenting wi...

Are you a curious person with a lot of ideas and little time? 
Anne-Laure Le Cunff can show you how to do it all. Anne-Laure is the founder of one of my favorite internet communities for curious minds, Ness Labs, a prolific writer, and a neuroscience PhD candidate. She’s also wri...

The next big idea is hiding in plain sight. It’s right here, scattered across the internet in incoherent fragments. Steph Smith, my guest for this episode, knows how to connect the dots. 
Steph Smith is a prolific online creator, host of the a16Z podcast, author of a book about b...