AI & I

Antidepressants changed my life.

I have OCD and antidepressants did what nearly a decade of therapy, meditation, and supplements couldn’t: they allowed me to live my life without being in a 24/7 spiral. (Bonus: they actually made therapy and meditation far more helpful once they...

You can build and run a one-person internet business that earns half a million in annual revenue—with AI.
Ben Tossell showed me exactly how in this episode. Ben is the founder of Ben’s Bites—one of the best daily AI newsletters out there, which I love reading every day—and an inv...

I made the greatest trade of my life with Jesse Beyroutey in 2019. We bought Nvidia shares when they were trading at $33. They’re worth nearly $800 today.
I sat down with Jesse to top that trade in 90 minutes using Gemini Pro 1.5’s incredible 1 million token context window—and ma...

You can break into Hollywood with a movie you made alone in your room without using a single camera. Dave Clark showed me how live on this show.
Dave Clark is a film director and commercial director with experience working with brands like HP and Intel who is now experimenting wi...

Are you a curious person with a lot of ideas and little time? 
Anne-Laure Le Cunff can show you how to do it all. Anne-Laure is the founder of one of my favorite internet communities for curious minds, Ness Labs, a prolific writer, and a neuroscience PhD candidate. She’s also wri...

The next big idea is hiding in plain sight. It’s right here, scattered across the internet in incoherent fragments. Steph Smith, my guest for this episode, knows how to connect the dots. 
Steph Smith is a prolific online creator, host of the a16Z podcast, author of a book about b...

You can make a video game without writing a single line of code. Logan Kilpatrick uses ChatGPT to show me how.
Logan is OpenAI’s first developer relations and advocacy hire. A big part of Logan’s job is supporting the community of builders using ChatGPT, DALL-E, and the OpenAI AP...

Dr. Gena Gorlin (https://twitter.com/Gena_I_Gorlin) is a clinical psychologist at UT Austin whose goal is to raise the ceiling on human potential. 
I sat down with her to discuss how ChatGPT has become a key tool in her quest for radical self-betterment.
In this episode, she feed...

Tyler Cowen is an economist who has been thinking about the impact of technology on life, work, and the economy for the past decade. He is a prolific writer behind the leading economic blog Marginal Revolution, a professor of economics at George Mason University, and the author o...

David Perell is one of the best known internet writers of his generation. 

He’s amassed almost a half million followers on X, hosts the popular podcast How I Write, and founded Write of Passage, which has taught thousands of students how to be digital writers.

We go deep on usi...

This show might be a first in the history of podcasts:
Researcher ⁠Geoffrey Litt⁠ and I built an app together using ChatGPTapp and Replit in under 60 minutes—while we talked.
We wanted to show how AI and ChatGPT change who gets to build software and how they usher in a world wher...

Sometimes ChatGPT is a copilot, sitting beside you, taking directions, and guiding you as you fly through your work. At other times, it’s a subordinate. It’s not just an assistant or a companion, but a trusted deputy, someone—or something—that’ll heed instructions and complete ta...